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The titration ladder is 0.25 0.5 1.0 1.7 2.4 mg/week, with each step usually held 2-4 weeks

It binds to hepatocyte growth factor (HGF) with high affinity and potentiates its activity at its receptor, c-Met

Ongoing Commitment: Optimal results typically require ongoing treatment, though protocols may be adjusted over time based on progress and goals

This phenomenon might be noticeable in the first few weeks of treatment or after dose increases, though this mechanism has not been specifically studied in GLP-1 clinical trials

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